BURGERSTEIN EPA capsules 500 mg 180 pieces

BURGERSTEIN EPA capsules 500 mg 180 pieces Swissmedic-approved specialist information # Burgerstein EPA capsules 500 mg Antistress AG Society for Health Protection composition Active ingredients: Piscis oleum corresp. Acida carboxylica omega-3 oligoinsaturata ut Acidum eicosapentaenoicum and Acidum docosahexaenoicum, alfa-tocopheroli. Excipients: int-rac-alfa-tocopherolum (E 307); Capsule shell: gelatin, Glycerolum (85 per centum, E 422), Sorbitolum liquidum crystallisabile 70% corresp. Sorbitolum (E 420) 28 mg per capsule. Dosage form and amount of active ingredient per unit 1 capsule contains: 500 mg fish oil with 150 mg omega-3 fatty acids equivalent to 90 mg Eicosapentaenoic acid (EPA) and 60 mg docosahexaenoic acid (DHA). Indications/applications As a dietary supplement to food for elevated blood lipid levels and for Ensuring the need for essential polyunsaturated Omega-3 fatty acids. Dosage/Application Adults and young people aged 14 and over As a dietary supplement, take 1 Burgerstein EPA capsule 500 mg 3 times daily taken with meals. The capsules are swallowed whole with a glass of water swallowed. Burgerstein EPA capsules 500 mg are not for use in adolescents and Intended for children under 14 years of age. Contraindications If you are hypersensitive to one of the active ingredients or one of the Excipients according to composition. Burgerstein EPA capsules 500 mg are intended for Disorders of fat digestion or fat emulsification in the small intestine, caused by gallbladder or pancreatic diseases, should not be taken. Warnings and precautions Caution is advised when taking anticoagulants at the same time The effect of which can be enhanced by Burgerstein EPA capsules 500 mg. Burgerstein EPA capsules 500 mg contain 28 mg sorbitol per capsule corresponding to 0.4 mg per kg for a body weight of 70 kg. The additive effect of concurrently administered sorbitol (or fructose) -containing medicines and taking sorbitol (or fructose) via the Food must be taken into account. The sorbitol content of orally administered drugs can influence the bioavailability of other medicines administered orally at the same time. Interactions The prolongation of bleeding time and the reduction of platelet counts Aggregation requires a review of anticoagulated patients (possibly Reducing the dosage of anticoagulants). Omega-3 fatty acids can lead to a gradual reduction in elevated levels Lead blood pressure values. This is at the dosage of antihypertensive drugs to be taken into account. Pregnancy/breastfeeding Burgerstein EPA capsules 500 mg should be used during pregnancy and Do not use during breastfeeding unless clearly necessary. Effects on the ability to drive and operate machines Burgerstein EPA capsules 500 mg have no influence on the ability to drive or the ability to operate machines. Adverse effects When evaluating undesirable effects, the following frequencies are used based on: Very common: (≥1/10); common: (≥1/100 to <1/10); uncommon: (≥1/1000 to <1/100); rare: (≥1/10,000 to <1/1000); very rare: (<1/10,000). Diseases of the gastrointestinal tract: Uncommon: Intolerance reactions in the gastrointestinal area, such as Diarrhea or abdominal pain may occur. This statement is based on the Experiences available to date with the active ingredients. The belching of fish oils and occasional nausea can be caused by... It is best to turn it off by consuming fish oils immediately before main meals be taken. Reporting of suspected side effects after approval is required great importance. It enables continuous monitoring of the Benefit-risk ratio of the drug. Health professionals are urged to report any suspicions new or serious side effects via the online portal ElViS (Electronic Vigilance System). You can find information about this at www.swissmedic.ch. Overdose So far there is nothing about an acute overdose of omega-3 fatty acids known. At very high doses (>4 g/d) over a longer period of time, a Prolongation of bleeding time and a decrease in omega-6 fatty acid levels noted. Properties/Effects ATC code: C10AX06 Mechanism of action The omega-3 fatty acids contained in Burgerstein EPA capsules 500 mg are essential fatty acids and cannot be synthesized in the body. The The body is therefore dependent on their exogenous supply. Cardiovascular system Omega-3 fatty acids have an endothelial protective effect and inhibit it Platelet aggregation, reduce fibrinogen formation and act plaque stabilizing and tends to lower blood pressure. The membrane flexibility of red blood cells is increased. Omega-3 fatty acids have a wide variety positive effects on blood lipids. In particular, increased serum triglycerides and triglyceride-rich VLDL are lowered by omega-3 fatty acids. In addition, there is also a reduction in total cholesterol, LDL cholesterol and lipoprotein (a). At the same time, HDL levels are increased. The formation of vasodilator nitrogen monoxide (NO) is promoted. nervous system Docosahexaenoic acid (DHA) is an important building block of brain and Nerve cells and the retina. Inflammation and immune function About the interaction with the enzymes lipoxygenase and cyclooxygenase Eicosapentaenoic acid (EPA) reduces the formation of proinflammatory substances Prostaglandins and leukotrienes from arachidonic acid. Eicosapentaenoic acid also reduces and inhibits the release of TNF-alpha Formation of IL-1. Pharmacodynamics No data available. Clinical effectiveness See mechanism of action. Pharmacokinetics Absorption The highly unsaturated substances contained in Burgerstein EPA capsules 500 mg Omega-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid become complete mainly absorbed in the upper part of the small intestine. Distribution Within 4 hours of ingestion, the omega-3 fatty acids are absorbed into the Free fatty acids and phospholipids of the plasma are incorporated and like fatty acids metabolized. After taking omega-3 fatty acids, higher levels can occur Tissue levels of EPA, especially in muscle tissue, of DHA in muscle, gastrointestinal tract and in the heart. Metabolism Omega fatty acids provide starting substances (precursor fatty acids) for the Synthesis of the following eicosanoids: prostaglandins (PG), prostacyclins (PGI), Thromboxanes (TXA) and Leukotrienes (LT). Made from omega-3 fatty acids Eicosanoids of the 3 series (PGI3 and PXA3). The amounts and types of eicosanoids formed depend on availability arachidonic acid or EPA and the activities of cyclooxygenase and lipoxygenase. There is a direct relationship between arachidonic acid and EPA Competition. The omega-3 and omega-6 fatty acids compete for the same Enzyme systems. A metabolism takes place between the two omega fatty acids but not taking place. Elimination The prostaglandins formed from the omega-3 fatty acids disappear quickly from the bloodstream. Lungs, liver, kidneys and the genital glands take them Preferably prostaglandins. The prostaglandins are produced from the carboxyl group in the organism by beta- Quickly broken down by oxidation. The numerous natural metabolites of the Prostaglandins are excreted in the urine. Kinetics of special patient groups No data available. Preclinical data There are none relevant to the use of Burgerstein EPA capsules 500 mg preclinical data available. Other information Durability The medicine can only be used up to the limit Brandd “EXP” on the container Date can be used. Special storage instructions Keep it tightly closed, dry and out of the reach of children Store at room temperature (15-25°C). Approval number 49417 (Swissmedic). Authorization holder Antistress AG, Society for Health Protection, 8640 Rapperswil-Jona. Status of information May 2020. Product name| Burgerstein EPA 500 mg —|— Gtin| 7680494170200 Batch number| 2408013 Expiry date| April 30, 2027 Manufacturer| Antistress Ltd Fluhstrasse 30 8640 Rapperswil [www.burgerstein.ch](//www.burgerstein.ch) Sales| ebi-pharm ag Lindachstrasse 8c 3038 Kirchlindach [www.ebi-pharm.ch](//www.ebi-pharm.ch) Patient Information — Description| Burgerstein EPA capsules 500 mg contain a concentrate Fish oils with various polyunsaturated, essential fatty acids (Omega-3 fatty acids), which are largely missing from our diet. The body requires these fatty acids to build hormone-like substances (Prostaglandins, thromboxanes, leukotrienes). Area of ​​application| Burgerstein EPA capsules 500 mg contain a concentrate Fish oils with various polyunsaturated, essential fatty acids (Omega-3 fatty acids), which are largely missing from our diet. The body requires these fatty acids to build hormone-like substances (Prostaglandins, thromboxanes, leukotrienes). A lack of Omega-3 fatty acids can cause the formation of certain Fat metabolism disorders can also be influenced.Burgerstein EPA capsules 500 mg are used as a dietary supplement to the diet at elevated levels Blood lipid levels and to ensure the need for unsaturated fatty acids. Application| Adults and young people aged 14 and over: As a dietary supplement 1 capsule is taken 3 times daily with meals. The capsules will Swallowed whole with a glass of water. Burgerstein EPA capsules are 500 mg not for use in adolescents and children under 14 years of age determined.Adhere to the instructions given in the package leaflet or from Dosage prescribed by your doctor. If you believe that If the medicine is too weak or too strong, talk to your doctor. Pharmacist or druggist or with your doctor, pharmacist or druggist. Composition/Ingredients| 1 capsule contains 500 mg of fish oil with 150 mg Omega-3 fatty acids corresponding to 18% eicosapentaenoic acid (EPA), 12% Docosahexaenoic acid (DHA), 5 mg vitamin E and excipients. Side effects| Rarely, intolerance reactions in the gastrointestinal Area, such as diarrhea or abdominal pain.Burping Fish oils and occasional nausea are best eliminated, by taking fish oils immediately before main meals.If you If you notice any side effects not described here, you should inform yourself Doctor, pharmacist or druggist or your doctor, pharmacist or druggist inform. Warnings| Burgerstein EPA capsules 500 mg are intended for disorders of the Fat digestion, caused by gallbladder or Pancreatic disease or hypersensitivity to one of the ingredients should not be used. Caution is advised taking medicines to thin the blood at the same time (Anticoagulation), as their effect is provided by Burgerstein EPA capsules 500 mg can be reinforced. Tell your doctor, pharmacist or druggist or your doctor, pharmacist or druggist if you have other illnesses suffer, have allergies or take other medicines (even those you bought yourself!) Take or apply externally. Use during pregnancy/breastfeeding During pregnancy Burgerstein EPA capsules 500 mg should not be used during breastfeeding become. Additions to the application| Further to note| Burgerstein EPA capsules 500 mg tightly closed Room temperature (15-25°C) dry and out of reach of children Store the medicine only up to the amount Brandd “Exp” on the container. specified date. Your doctor can provide you with further information. Pharmacist or druggist or your doctor, pharmacist or druggist. This People have detailed specialist information. Dosage form| Hard capsule Application route| oral What packs are available?| Packs of 60 and 180 capsules. Where is the product available?| In pharmacies and drugstores, without a doctor Prescription. Storage note| Burgerstein EPA capsules 500 mg tightly closed Room temperature (15-25°C) dry and out of reach of children store. Last check by Swissmedic| November 2006 Patient Information| Pack size| 180 capsules