DEXERYL cream TB 250 g

11,15 CHF

SKU: 04824206 Category: Tag:

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DEXERYL cream TB 250 g Swissmedic-approved specialist information # Dexeryl®, cream Pierre Fabre Pharma AG composition active ingredients Glycerolum, Vaselinum album, Paraffinum liquidum. Excipients Acidum stearicum, Glyceroli monostearas 40-55, Ciclometiconum, Dimeticonum, Macrogolum 600, Trolaminum, Propylis parahydroxybenzoas (1mg/g), aqua purificata Dosage form and amount of active ingredient per unit 1 g of Dexeryl cream contains 0.15 g of glycerin, 0.08 g of petroleum jelly and 0.02 g paraffin oil. Indications/applications Treatment of dry skin in certain dermatoses, for example ichthyosis. Dosage/Application Adults and children: Cream twice daily or more often if necessary in a thin layer Apply a layer to the areas to be treated. Contraindications Hypersensitivity to the active ingredients or one of the excipients according to composition. Warnings and precautions Do not take. The product should not be used on infected wounds or under occlusive dressings be applied. This medicine contains propyl parahydroxybenzoate and may cause allergic reactions Trigger reactions (possibly delayed). Interactions No interaction studies have been conducted. Pregnancy/breastfeeding Pregnancy There is no information on how to use this medicine pregnant women. Since systemic exposure is negligible, will have no effect on the course of the pregnancy or the unborn child Expecting child. Dexeryl cream can be used during pregnancy become. Breastfeeding There is no information on how to use this medicine breastfeeding women. Taking into account the type of active ingredients no risks expected. However, it is recommended to use Dexeryl cream during Do not use on the breast area while breastfeeding. Fertility Since systemic exposure to glycerin, petroleum jelly and liquid paraffin is negligible, no effects on fertility are expected. Effects on the ability to drive and operate machines Dexeryl, cream has no influence on the ability to drive or to operate machines. Adverse effects Below are the adverse reactions by organ system class (MedDRA) and frequency listed in the clinical studies or after the Brandt launch using Dexeryl has been reported. The frequencies are defined as follows: Very common (≥1/10); common (≥1/100; <1/10); uncommon (≥1/1,000; <1/100); rare (≥1/10,000; <1/1,000), very rare (< 1/10,000), not known (based mainly on spontaneous reports Brandt surveillance, exact frequency can be determined based on available data not be appreciated). Diseases of the skin and subcutaneous tissue Uncommon: Erythema, pruritus, rash, urticaria, dermatitis, eczema, Irritation, pain at the application site Not known: burning sensation. Reporting of suspected side effects after approval is required great importance. It enables continuous monitoring of the Benefit-risk ratio of the drug. Relatives of Health professionals are asked to report any suspicion of a new or serious side effects via the online portal ElViS (Electronic Vigilance System). Information about this can be found at www.swissmedic.ch. Overdose An overdose is possible due to the method of application and the small amount systemic absorption unlikely. Properties/Effects ATC code: D02AX Mechanism of action The mechanisms of action of Dexeryl cream are as follows: * Reduction of moisture loss: Vaseline and paraffin oil form a lipid film that limits the moisture loss of the stratum corneum and allows water-soluble and hygroscopic substances to be retained therein. * Improved moisturization of the superficial layers of the skin through the hygroscopic effect of glycerin and through the penetration of glycerin into the epidermis. These properties, which are used in pharmacoclinical studies Validated models have been shown to promote the recovery of the moisture content and the protective function of the skin, causing irritation, Itching and scratching are reduced. Pharmacodynamics Clinical effectiveness All properties were evaluated as part of a clinical study Form of dry skin (ichthyosis) objectified. As part of this Study has shown that Dexeryl cream reduces the symptomatology according to the SRRC (Scaling, Roughness, Redness, Cracks fissures) Score significantly improved: 65% of patients under treatment with Dexeryl cream versus 50% under Treatment with a cream base was associated with a reduction in the SRRC score by at least 50%. Pharmacokinetics Not applicable. Preclinical data The preclinical data show that Dexeryl is well tolerated by the skin, Cream that has also been confirmed in humans. The cream doesn't work irritating to the eyes. It has no phototoxic potential, shows im However, animal experiments have weak potential to increase sensitization and photosensitization. This risk can occur in humans as be considered negligible since there is no UV absorption above 290 nm. Other information Durability The medicine can only be used up to the limit Brandd “EXP” on the container Date can be used. Shelf life after opening * Tube: 6 months * Pump bottle: 90 days Special storage instructions Store at room temperature (15-25°C). Store in the original packaging. Keep the container tightly closed. Keep out of the reach of children. Approval number 60404 (Swissmedic) Authorization holder Pierre Fabre Pharma AG, Allschwil Status of information November 2020[/vc_column_text][/vc_column_inner][/vc_row_inner][/vc_column][/vc_row][vc_row type="full_width_background" full_screen_row_position="middle" column_margin="90px" equal_height="yes" content_placement="middle" column_direction="default" column_direction_tablet="default" column_direction_phone="default" bg_color="#ffffff" scene_position="center" text_color="dark" text_align="left" row_border_radius="none" row_border_radius_applies="bg" overflow="visible" overlay_strength="0.5" gradient_direction="top_to_bottom" shape_divider_position="bottom" bg_image_animation="none" shape_type="straight_section" gradient_type="default"][vc_column column_padding="padding-4-percent" column_padding_tablet="no-extra-padding" column_padding_phone="no-extra-padding" column_padding_position="right" column_element_direction_desktop="default" column_element_spacing="10px" desktop_text_alignment="default" tablet_text_alignment="default" phone_text_alignment="default" background_color_opacity="1" background_hover_color_opacity="1" column_backdrop_filter="none" column_shadow="none" column_border_radius="none" column_link_target="_self" column_position="default" zindex="100" gradient_direction="left_t_to_right_b" overlay_strength="0.3" width="1/2" tablet_width_inherit="default" animation_type="default" bg_image_animation="none" border_type="simple" column_border_width="none" column_border_style="solid" offset="vc_col-xs-12"][vc_column_text css_animation="none" css=".vc_custom_1739545936729{margin-bottom: 10px !important;}" text_direction="default"]

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