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BURGERSTEIN Vitamin E soft caps 100 IU Ds 100 pieces Swissmedic-approved specialist information # Burgerstein Vitamin E ANTI-STRESS AMZV composition Active ingredient: Natural vitamin E. Excipients: Excip. per caps. Galenic form and amount of active ingredient per unit Burgerstein Vitamin E 100 IU 1 capsule contains d-alpha-tocopherol 67.1 mg corresp. 100 IU Vitamin E Excipients: Excip. per caps. Burgerstein Vitamin E 400 IU 1 capsule contains d-alpha-tocopherol 268.4 mg corresp. 400 IU Vitamin E Excipients: Excip. per caps. Indications/applications Prophylaxis: To cover increased needs (e.g. in diets with a high Proportion of polyunsaturated fatty acids). Therapy: Prevention of vitamin E deficiency due to absorption disorders. Vitamin E administration can also be tried as an adjuvant for claudication intermittent, dyslipoproteinemia with reduced HDL cholesterol levels increased LDL cholesterol. Dosage/Application Burgerstein Vitamin E 100 IU Adults: One capsule one to four times daily during meals take. Burgerstein Vitamin E 400 IU Adults: 1 capsule daily (to be taken with a meal) or after Doctor’s prescription. The use and safety of Burgerstein Vitamin E 100 IU/400 IU Children and young people have not yet been tested. Contraindications In case of hypersensitivity to the active ingredient or one of the excipients. Warnings and precautions High doses of vitamin E can increase the effects of anticoagulants. In anticoagulated patients, the coagulation status must be carefully monitored become. Interactions Very high doses of vitamin E have been shown in animal experiments Restricted absorption of vitamins A and K. Oral iron may decrease the absorption of vitamin E if both are given at the same time. In this case, it is recommended to take these two preparations at the same time To be taken approximately 4 hours apart. High doses of vitamin E can increase the effects of anticoagulants. Pregnancy/breastfeeding Animal studies with vitamin E have shown no evidence of teratogenic effects effects result. Vitamin E can be taken in an amount that corresponds to the daily requirement. be taken. With daily doses, like those with Burgerstein Vitamin E capsules 100 IU and Burgerstein Vitamin E capsules 400 IU are administered There are no controlled studies in animals or pregnant women. Although until There are no known serious, adverse consequences today, the medicine should be used be used with caution during pregnancy. The preparation should be used during breastfeeding only if the potential benefit is that Risk for the newborn exceeds. Effects on the ability to drive and operate machines Burgerstein Vitamin E capsules 100 IU and Burgerstein Vitamin E capsules 400 I.E. have no influence on the ability to drive or to operate machines. Adverse effects Daily doses of up to 800 mg usually do not cause any undesirable effects Effects. It only occasionally occurs with doses in the gram range temporary gastrointestinal complaints (bloating, diarrhea or nausea). An increased creatine kinase activity in the serum and an increase in creatine in the Urine (above 100 mg/24 hours, the upper limit of normal). been reported. Apart from that, there are no other changes Laboratory parameters reported following vitamin E administration been. Overdose The recommended doses of vitamin E do not cause hypervitaminosis. Properties/Effects ATC code: A11HA03 Vitamin E is an antioxidant, so it reduces oxygen consumption Metabolism and provides other physiological active ingredients Oxidation protection. It contributes to the construction of all tissues derived from the mesoderm and is involved in maintaining their function. Vitamin E is fat-soluble and is only absorbed in the intestine if fat absorption is intact. At Disturbance of fat absorption, e.g. in atresia of the biliary tract Absorption impaired. Pharmacokinetics Absorption Vitamin E absorption probably occurs in the middle section of the small intestine through a non-saturable, passive diffusion process. The Absorption into the tissue occurs via the LDL receptors and is direct proportional to the logarithm of vitamin E intake. The vitamin E pool is located between 3.4-8.0 g. Natural d-alpha-tocopherol is significantly better absorbed and retained as the synthetic dl-alpha-tocopherol. Distribution The highest vitamin E concentrations can be found in fatty tissue and in the adrenal glands can be found. The special advantages of natural d-alpha Tocopherols compared to its synthetic variants (dl-alpha-tocopherol and their acetates) have been proven in several studies. Metabolism Vitamin E is absorbed by the liver and delivered to the low density lipoproteins (LDL). Most of the absorbed tocopherols are unchanged in which transports tissue. Elimination After excretion in the bile, vitamin E is released along with the The unabsorbed portion of dietary tocopherol is excreted in the feces. This is the most important excretion route. Preclinical data No relevant mutagenic, carcinogenic and teratogenic findings were found for vitamin E Effects can be found. Other information Durability The medicine can only be used up to the limit Brandd “EXP” on the container Date can be used. Special storage instructions Keep it tightly closed, dry and out of the reach of children Store at room temperature (15-25°C). Approval number 38407, 44562 (Swissmedic). Authorization holder Antistress AG, Society for Health Protection, 8640 Rapperswil-Jona. Status of information December 2006. Product name| Burgerstein Vitamin E 100 iU —|— Gtin| 7680384070139 Batch number| 2303006 Expiry date| August 31, 2026 Manufacturer| Antistress Ltd Fluhstrasse 30 8640 Rapperswil [www.burgerstein.ch](//www.burgerstein.ch) Sales| ebi-pharm ag Lindachstrasse 8c 3038 Kirchlindach [www.ebi-pharm.ch](//www.ebi-pharm.ch) Patient Information — Description| Burgerstein Vitamin E capsules 100 IU and Burgerstein Vitamin E-capsules 400 IU contain natural vitamin E from vegetable oils. Vitamin E is an essential nutrient. Area of application| Burgerstein Vitamin E capsules 100 IU and Burgerstein Vitamin E capsules 400 IU contain natural vitamin E from vegetable oils. Vitamin E is an essential nutrient. Burgerstein Vitamin E capsules 100 IU and Burgerstein Vitamin E capsules 400 IU are used for Covering increased needs (e.g. in diets with a high Proportion of polyunsaturated fatty acids), for prevention and treatment a vitamin E deficiency due to insufficient intake with the usual food or due to metabolic disorders. Vitamin E can also Lipid metabolism disorders can be tried. Application| Adults: Burgerstein Vitamin E capsules 100 IU: Take 1–4× 1 capsule daily during meals, together with a glass Water.Burgerstein Vitamin E capsules 400 IU: Unless you ask otherwise If prescribed, swallow 1 capsule daily during a meal, together with a glass of water.The use and safety of Burgerstein Vitamin E capsules 100 IU and Burgerstein Vitamin E capsules 400 IU Children and young people have not yet been examined as to why this is the case Medicines should not be taken by you. Stick to the instructions given in stated in the package leaflet or prescribed by the doctor Dosage. If you think the medicine is too weak or too strong, So talk to your doctor, pharmacist or druggist or with yours Doctor, pharmacist or druggist. Composition/Ingredients| Burgerstein Vitamin E capsules 100 IU: 1 capsule contains 100 IU of natural vitamin E, excipients. Side effects| It only occasionally occurs with doses in the gram range temporary gastrointestinal complaints (bloating, diarrhea or Nausea).If you notice any side effects not described here, you should consult your doctor, pharmacist or druggist, Inform your pharmacist or druggist. Warnings| Burgerstein Vitamin E capsules 100 IU and Burgerstein Vitamin E-capsules 400 IU must not be used if you are on one of the Ingredients are allergic.Patients taking anticoagulants If you are taking medication, Burgerstein Vitamin E capsules 100 IU and Burgerstein Vitamin E capsules 400 IU only after consultation take it with your doctor. The simultaneous intake of Iron preparations can reduce the effect of Burgerstein Vitamin E capsules 100 IU. and Burgerstein Vitamin E capsules 400 IU. Therefore there should be between taking iron supplements and Burgerstein vitamin E capsules 100 IU. and Burgerstein Vitamin E capsules 400 IU about 4 hours apart lying.Inform your doctor, pharmacist or druggist, Your pharmacist or druggist if you suffer from other illnesses, Have allergies or are taking other medicines (including those you bought yourself!) or apply externally. Use during pregnancy/breastfeeding In a quantity that daily requirements, you are allowed to take vitamin E during pregnancy and take while breastfeeding. With daily doses, like those with Burgerstein Vitamin E capsules 100 IU and Burgerstein Vitamin E capsules 400 IU However, you should only use this medicine after consultation take with your doctor. Further to note| Burgerstein Vitamin E capsules 100 IU and Burgerstein Vitamin E capsules 400 IU should be kept out of the reach of children as well closed, dry and stored at room temperature between 15-25°C The medicine may only be used up to the amount Brandd “EXP” on the container. specified date. Your doctor can provide you with further information. Pharmacist or druggist or your doctor, pharmacist or druggist. This People have detailed specialist information. Dosage form| Hard capsule Application route| oral What packs are available?| Packs of 100 Vitamin E capsules 100 IU packs of 100 vitamin E capsules 400 IU Where is the product available?| In pharmacies and drugstores, without a doctor Prescription. Storage note| Burgerstein Vitamin E capsules 100 IU and Burgerstein Vitamin E-capsules 400 IU should be kept out of the reach of children as well closed, dry and stored at room temperature between 15-25°C become. Last check by Swissmedic| December 2006 Pack size| 100 capsules
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